Creation of artificial cellulosomes on DNA scaffolds by zinc finger protein-guided assembly for efficient cellulose hydrolysis.

نویسندگان

  • Qing Sun
  • Bhawna Madan
  • Shen-Long Tsai
  • Matthew P DeLisa
  • Wilfred Chen
چکیده

For the first time, artificial cellulosome structures were created on DNA scaffolds based on zinc finger protein (ZFP)-guided assembly. These resulting two-component cellulosome structures exhibited enhancement in cellulose hydrolysis compared to the non-complexed mixture depending on the number of CBMs and cellulases assembled.

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عنوان ژورنال:
  • Chemical communications

دوره 50 12  شماره 

صفحات  -

تاریخ انتشار 2014